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In enzymology, a GDP-mannose 4,6-dehydratase () is an mannosyltransferase enzyme that catalyzes the chemical reaction :GDP-mannose GDP-4-dehydro-6-deoxy-D-mannose + H2O Hence, this enzyme has one substrate, GDP-mannose, and two products, GDP-4-dehydro-6-deoxy-D-mannose and H2O. This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming). Other names in common use include guanosine 5'-diphosphate-D-mannose oxidoreductase, guanosine diphosphomannose oxidoreductase, guanosine diphosphomannose 4,6-dehydratase, GDP-D-mannose dehydratase, GDP-D-mannose 4,6-dehydratase, Gmd, and GDP-mannose 4,6-hydro-lyase. This enzyme participates in fructose and mannose metabolism. It employs one cofactor, NAD+. ==Structural studies== As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes , , , , and . 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「GDP-mannose 4,6-dehydratase」の詳細全文を読む スポンサード リンク
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